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Pioneering Medicines: Director / Sr. Director – Immunology Drug Discovery and Translational Research

Pioneering Medicines: Director / Sr. Director – Immunology Drug Discovery and Translational Research

CompanyFlagship Pioneering
LocationCambridge, MA, USA
Salary$Not Provided – $Not Provided
TypeFull-Time
DegreesPhD
Experience LevelSenior, Expert or higher

Requirements

  • Ph.D., with demonstrated evidence of success e.g. through impactful publication/s
  • 6+ years of industry experience in drug discovery and/or translational research.
  • Deep understanding of translational research including biomarker discovery, PK/PD/efficacy relationships, dose predictions, and supporting assets into early clinical development
  • Experience generating proof-of-concept for novel clinical biomarker assays, supporting their implementation on clinical trials
  • Experience delivering data and documentation supporting IND/CTA regulatory filing
  • Scientific expertise in immunology will be beneficial for this position.
  • Ability and interest to work across multiple therapeutic areas and modalities
  • Prior experience managing a team of PhD and Non-PhD scientists

Responsibilities

  • Represent the translational sciences function on drug discovery project teams for a portfolio of programs. Accountable to support asset progression from early discovery through to the clinic
  • Serve as a research program lead on one or more drug discovery projects. Responsible for matrixed leadership of cross-functional research team deliverables
  • Contribute to building the immunology portfolio, through identification and championing of new targets and approaches
  • Manage, mentor and grow a team of direct reports
  • Participate in external partnerships with Flagship Platform companies and large pharma partners
  • Develop platforms, identify CROs and external collaborators to grow the translational sciences capabilities
  • Support research operational strategy and implementation, contributing to the overall management and infrastructure of a growing research team

Preferred Qualifications

  • Postdoctoral experience
  • Demonstrated expertise in identifying and validating new targets in immunology
  • Experience working in multiple drug discovery functions in early and late stage programs
  • Ability to leverage cross-functional approaches to derive translational insights. A strong understanding of translational bioinformatics is highly desirable
  • Experience leading or participating in discussions with KOLs, due diligence assessments and cross-industry collaborations