Principal Scientist – Cell Therapy In Vivo Pharmacology
| Company | Bristol Myers Squibb |
|---|---|
| Location | Seattle, WA, USA |
| Salary | $153680 – $186200 |
| Type | Full-Time |
| Degrees | Bachelor’s, Master’s, PhD |
| Experience Level | Senior, Expert or higher |
Requirements
- Bachelor’s Degree + 8+ years of academic and / or industry experience
- Master’s Degree + 6+ years of academic and / or industry experience
- Ph.D. or equivalent advanced degree in the Life Sciences + 4+ years of academic and / or industry experience
Responsibilities
- Lead functional workstreams on highly matrixed cell therapy research project teams from target concept to IND
- Mentor/supervise pharmacology team members to support in vivo experimentation, including planning and directing lab research
- Possess broad experience in the development and execution of tumor models, including syngeneic and xenograft models, and / or T cell-driven immune response models
- Demonstrate expertise in multi-parameter flow cytometry (10-plus colors), immune cell functional assays (e.g. proliferation, cytokine production, cytotoxicity), and the fields of T cell biology and cellular immunology
- Independently author study reports, technical protocols, publications and documents to support regulatory and patent submissions, demonstrating broad experience in scientific writing
- Present complex concepts to a range of audiences including governance and departmental meetings
- Apply advanced technical knowledge to guide the development of cutting-edge immune cell therapies
- Excel in a fast-paced team environment, meet deadlines, and prioritize work on multiple projects while fostering open and productive scientific communication and collaboration
Preferred Qualifications
- Ph.D. or equivalent advanced degree in Immunology or related field
- 6+ years of academic and industry experience
- Experience with preclinical assessment of therapeutic candidates including cell-based therapies, immunotherapies, and drug combination studies
- Knowledge of pharmacokinetic and pharmacodynamic models to evaluate candidate therapeutics
- Familiarity with gene editing technologies and delivery methods (e.g., adeno-associated viral vectors, non-viral delivery, CRISPR gene editing)
- Ability to write and manage IACUC protocols, own compliance with these and other protocols, and identify potential gaps
- Track record of successful internal and external scientific collaborations
- Experience supervising technical staff to lead early-stage projects