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Bioinformatics Scientist

Bioinformatics Scientist

CompanyGuardant Health
LocationPalo Alto, CA, USA
Salary$Not Provided – $Not Provided
TypeFull-Time
DegreesPhD
Experience LevelSenior, Expert or higher

Requirements

  • Ph.D. in Bioinformatics, Computational Biology, Statistics, Genomics or related fields.
  • Established scientific expertise, demonstrated through peer-reviewed publications and/or contributions to successful product development in the biotech industry.
  • In-depth knowledge of modern genomic tools and pipelines for processing and analyzing primary data, including somatic and structural variant detection.
  • Extensive experience in next-generation sequencing (NGS) data analysis, including DNA, RNA, or epigenetic analysis.
  • Proficiency in scripting languages (e.g., Python, R) and Linux shell environment, with a strong foundation in data analysis and interpretation.
  • Strong written and verbal communication skills, with a proven ability to effectively convey complex scientific concepts and present clearly and effectively to stakeholders across organizations.
  • Ability to thrive in a fast-paced startup environment, delivering high-quality results under tight timelines.
  • Strong analytical and organizational skills, with the ability to synthesize complex concepts, drive projects forward, and maintain attention to detail.
  • Collaborative team player, adept at working cross-functionally and across institutions to achieve shared goals.

Responsibilities

  • Work with large, complex data sets.
  • Tend to non-routine analysis problems, applying deep epigenetic knowledge to conduct end-to-end analysis of epigenetic cell-free nucleic acid NGS data.
  • Develop or apply statistical methods and procedures to evaluate and validate Guardant Health technologies.
  • Systematically leverages external innovation ideas and expertise to address technology gaps and advance the Guardant Health’s business.
  • Provide analytical support on individual samples and research activities.
  • Deliver analytical support for clinical operations in compliance with CLIA and CAP regulatory standards.
  • Analyze genomic data from clinical patients and external annotation sources to improve the accuracy and quality of reporting.
  • Develop scripts for research and development activities, and leverage cutting edge AI methods to continuously improve efficiency.
  • Communicate research results through presentations and project reports as well as scientific publications.

Preferred Qualifications

  • Experience in developing novel or custom algorithms for NGS data interpretation.
  • Direct experience working with epigenomic data.