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Computational Biologist – Bioimage Analysis
Company | Chan Zuckerberg Biohub |
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Location | San Francisco, CA, USA |
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Salary | $138000 – $148500 |
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Type | Full-Time |
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Degrees | PhD |
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Experience Level | Mid Level, Senior |
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Requirements
- Recent (< 2 years) PhD. in Biology, Biophysics, Computer Science, Engineering, or related technical field
- 4+ years of experience in Python and relevant image processing libraries (e.g. numpy, scipy, skimage, napari)
- 4+ years experience in microscopy applied to biological systems (fluorescence and/or label-free modalities)
- Experience deploying advanced methods for segmentation and quantification of biological images (e.g. Cellpose, Segment Anything, Cellprofiler, etc.)
- A track record of impactful publications demonstrating experience with extracting biological insights from imaging data
- Excellent problem-solving skills and ability to work in an interdisciplinary environment;
- Excellent written and verbal communication skills
- Excellent documentation skills
Responsibilities
- Collaborate closely with Biologists, Computer Scientists, and Optical Engineers to quantify observations from large-scale phenotypic screens and discover new biology
- Manage the creation of and analysis pipelines for large-scale imaging datasets (100s TB)
- Generate and test hypotheses using imaging data
- Identify statistically significant observations from complex biological phenotypes
- Lead innovative research and contribute to top-tier publications and conference presentations
- Mentor junior scientists and foster a collaborative, continuous-learning environment
Preferred Qualifications
- Experience deploying code on high-performance computing and distributed systems
- Familiarity with Next-Generation-File-Formats (e.g. OME-ZARR)
- Experience with pipelining packages (snakemake / nextflow) or pipelining automation
- Familiarity with image acquisition pipeline (µManager)
- Familiarity with fundamental cell biology, such as signaling pathways or organelles
- Experience with high-throughput phenotypic assays (e.g. CRISPR screening, multiplexed imaging, spatial omics)