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Computational Biologist – Bioimage Analysis

Computational Biologist – Bioimage Analysis

CompanyChan Zuckerberg Biohub
LocationSan Francisco, CA, USA
Salary$138000 – $148500
TypeFull-Time
DegreesPhD
Experience LevelMid Level, Senior

Requirements

  • Recent (< 2 years) PhD. in Biology, Biophysics, Computer Science, Engineering, or related technical field
  • 4+ years of experience in Python and relevant image processing libraries (e.g. numpy, scipy, skimage, napari)
  • 4+ years experience in microscopy applied to biological systems (fluorescence and/or label-free modalities)
  • Experience deploying advanced methods for segmentation and quantification of biological images (e.g. Cellpose, Segment Anything, Cellprofiler, etc.)
  • A track record of impactful publications demonstrating experience with extracting biological insights from imaging data
  • Excellent problem-solving skills and ability to work in an interdisciplinary environment;
  • Excellent written and verbal communication skills
  • Excellent documentation skills

Responsibilities

  • Collaborate closely with Biologists, Computer Scientists, and Optical Engineers to quantify observations from large-scale phenotypic screens and discover new biology
  • Manage the creation of and analysis pipelines for large-scale imaging datasets (100s TB)
  • Generate and test hypotheses using imaging data
  • Identify statistically significant observations from complex biological phenotypes
  • Lead innovative research and contribute to top-tier publications and conference presentations
  • Mentor junior scientists and foster a collaborative, continuous-learning environment

Preferred Qualifications

  • Experience deploying code on high-performance computing and distributed systems
  • Familiarity with Next-Generation-File-Formats (e.g. OME-ZARR)
  • Experience with pipelining packages (snakemake / nextflow) or pipelining automation
  • Familiarity with image acquisition pipeline (µManager)
  • Familiarity with fundamental cell biology, such as signaling pathways or organelles
  • Experience with high-throughput phenotypic assays (e.g. CRISPR screening, multiplexed imaging, spatial omics)