Head of Antibody Drug Conjugates – Biologics Engineering
| Company | AstraZeneca |
|---|---|
| Location | Waltham, MA, USA, Gaithersburg, MD, USA |
| Salary | $208389 – $312000 |
| Type | Full-Time |
| Degrees | PhD |
| Experience Level | Expert or higher |
Requirements
- PhD in Biochemistry, Protein Engineering or related scientific discipline
- 10+ years of experience in building and leading high-performing ADC and Protein Engineering teams
- Proven ability to think strategically, act decisively, collaborate effectively and drive team performance
- Extensive track record of advancing numerous ADC therapeutics from discovery to the clinic, contributing to the pipeline of Big Pharma or major Biotech
- Recognized as a subject matter expert in next-generation ADC platform technologies, protein and linker engineering, site-specific conjugation, novel warhead development, and utilization of diverse formats such as traditional and bispecific antibodies, fragments, and different protein scaffolds
- Strong external reputation as an industry leader, evidenced by high-impact publications, presentations, and scientific community engagement
- Deep expertise in all aspects of ADC design, non-clinical characterization, and manufacturing
- Ability to advance projects against accelerated timelines, define clear go/no-go decision points, with a sharp focus on execution
- Exceptional communication skills, highly effective in interacting with key internal and external stakeholders
- Demonstrated passion for, and a track record of talent recruitment and development
Responsibilities
- Establish strategy, direction, and objectives for the development of next-generation ADC technologies
- Provide scientific leadership, mentorship, and technical guidance to a diverse team of scientists responsible for a robust ADC and RC biotherapeutics portfolio
- Drive innovation in ADC and RC across oncology and other therapeutic areas
- Act as a subject matter expert in Protein Engineering/Bioconjugation for targeted delivery modalities
- Represent Biologics Engineering in cross-functional collaborations to accelerate the discovery of groundbreaking medicines
- Ensure the delivery of a rich pipeline of drug candidates and other Biologics Engineering organizational priorities
- Foster a culture of transparency, innovation, and creativity, leading to new opportunities for the company and creation of intellectual property
- Partner with Business Development to pursue investments that enhance Biologics Engineering strategy
- Maintain a high degree of awareness of internal and external technology developments in the targeted delivery space
- Manage priorities, resources, growth, and investments aligned with the Biologics Engineering strategy
- Attract and develop talent to strengthen the team
Preferred Qualifications
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No preferred qualifications provided.