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Senior Research Associate II – Preclinical Development
Company | ArsenalBio |
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Location | San Bruno, CA, USA |
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Salary | $96700 – $118500 |
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Type | Full-Time |
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Degrees | Bachelor’s, Master’s |
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Experience Level | Senior |
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Requirements
- Masters in Cell or Molecular Biology, Biological Sciences or a related field with 2+ years industry experience, or Bachelors in a related field with 4+ years industry experience
- Excellent mammalian cell culture skills
- Experience with multi-colour flow cytometry, panel design, and data analysis
- Ability to quickly adapt and learn new skills for changing research priorities
- Demonstrated ability to work as a team player in a collaborative environment and coordinate tasks across multiple projects to meet deadlines
- Strong organizational skills, record keeping, and interpersonal communication skills (verbal and written)
- Flexible mind with the ability to think outside the box, creative approach to problem-solving
- Willingness to accept responsibilities outside of initial job description
- Passion for your work
- A positive attitude
Responsibilities
- Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products across multiple pipeline programs
- Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection
- Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization
- Support engineered T cell production activities (e.x. gene editing, T cell culture, cryopreservation, cell thawing)
- Culture both engineered primary T cell and suspension/adherent cell lines
- Support IND-enabling preclinical studies
- Assist effectively on cross-functional activities for project teams, including hand-offs, data analysis, and presenting at project meetings
- Maintain an up-to-date and detailed electronic lab notebook
- Coordinate tasks across multiple projects and teams, demonstrating prioritization and planning
- Execute and interpret experiments effectively in line with project timelines and goals
Preferred Qualifications
- Experience with primary T cell culture
- Experience with CRISPR gene editing and cell engineering workflows
- Experience with Incucyte live cell imager
- Experience with semi-automated pipetting workflows (e.x. Integra VIAFLO)