Senior Scientist-Functional Genomics
Company | Amgen |
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Location | San Bruno, CA, USA |
Salary | $135882 – $160726 |
Type | Full-Time |
Degrees | Bachelor’s, Master’s, PhD, JD, MD |
Experience Level | Senior |
Requirements
- Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
- Master’s degree and 3 years of relevant scientific experience
- Bachelor’s degree and 5 years of relevant scientific experience
Responsibilities
- Conduct impactful high throughput screening and profiling approaches for target discovery
- Help identify and implement new technologies to accelerate discovery
- Develop and execute downstream mechanistic assays to validate and advance targets
- Collaborate closely with disease area, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert
- Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums
Preferred Qualifications
- Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines
- Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals
- Hands-on expertise conducting and delivering complex screening campaigns for discovery
- Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry
- Expertise with molecular and cell biology tools such as antibodies, CRISPR, overexpression constructs, lentivirus, various approaches for cell engineering
- Experience with genomic perturbation at scale using cell lines and primary cells
- Proficiency in programming (e.g. in R/Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets and generation of custom computational pipelines
- Strong written, verbal, and oral communication skills and ability to thrive in cross-functional settings
- Experience in managing and coordinating team efforts