Posted in

Senior Scientist-Functional Genomics

Senior Scientist-Functional Genomics

CompanyAmgen
LocationSan Bruno, CA, USA
Salary$135882 – $160726
TypeFull-Time
DegreesBachelor’s, Master’s, PhD, JD, MD
Experience LevelSenior

Requirements

  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
  • Master’s degree and 3 years of relevant scientific experience
  • Bachelor’s degree and 5 years of relevant scientific experience

Responsibilities

  • Conduct impactful high throughput screening and profiling approaches for target discovery
  • Help identify and implement new technologies to accelerate discovery
  • Develop and execute downstream mechanistic assays to validate and advance targets
  • Collaborate closely with disease area, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert
  • Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums

Preferred Qualifications

  • Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines
  • Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals
  • Hands-on expertise conducting and delivering complex screening campaigns for discovery
  • Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry
  • Expertise with molecular and cell biology tools such as antibodies, CRISPR, overexpression constructs, lentivirus, various approaches for cell engineering
  • Experience with genomic perturbation at scale using cell lines and primary cells
  • Proficiency in programming (e.g. in R/Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets and generation of custom computational pipelines
  • Strong written, verbal, and oral communication skills and ability to thrive in cross-functional settings
  • Experience in managing and coordinating team efforts