Senior Scientist – Fungal Synthetic Biology
Company | Spark Climate Solutions |
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Location | Belmont, MA, USA |
Salary | $Not Provided – $Not Provided |
Type | Full-Time |
Degrees | PhD |
Experience Level | Senior |
Requirements
- PhD in microbiology, mycology, molecular biology, biochemistry, synthetic biology, or a related field.
- Authorized to work in the U.S. without sponsorship.
- Expertise in filamentous fungi genetics with hands-on experience across multiple species.
- Proven success in fungal genetic engineering (e.g., DNA delivery, genome editing, CRISPR, transposons) and molecular biology techniques (e.g., cloning, NGS, protein expression).
- Strong track record of rigorous, high-quality scientific output and record-keeping.
- Experience mentoring research staff and leading scientific initiatives.
- Comfort with lab automation and high-throughput screening approaches.
- Strong analytical skills and the ability to reason from first principles.
- Creative problem-solving mindset with adaptability to shifting priorities.
- Excellent communication and collaboration skills, with the ability to work independently and in teams.
- Passion for impactful research aligned with our mission.
Responsibilities
- Develop and optimize methods for studying and engineering various filamentous fungi.
- Design, construct, and test plasmids, genetic parts, and genome-wide perturbation libraries (e.g., transposons, Targetrons, CRISPR).
- Execute high-throughput cloning methodologies (Golden Gate, isothermal assembly, SLiCE, etc.) and next-generation sequencing (NGS) assays.
- Discover and characterize novel fungal genetic elements.
- Collaborate with engineers to integrate automation and high-throughput systems.
- Stay at the forefront of fungal genetics research, sourcing and implementing cutting-edge techniques.
- Manage and mentor research staff, ensuring rigorous experimental execution.
- Maintain meticulous documentation, write SOPs, and prepare internal reports and scientific publications.
- Effectively communicate findings internally and externally through presentations and manuscripts.
Preferred Qualifications
- Experience with microscopy, FACS, or microfluidics methods.
- Experience with isolation of environmental fungal samples.