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Senior Scientist – Fungal Synthetic Biology

Senior Scientist – Fungal Synthetic Biology

CompanySpark Climate Solutions
LocationBelmont, MA, USA
Salary$Not Provided – $Not Provided
TypeFull-Time
DegreesPhD
Experience LevelSenior

Requirements

  • PhD in microbiology, mycology, molecular biology, biochemistry, synthetic biology, or a related field.
  • Authorized to work in the U.S. without sponsorship.
  • Expertise in filamentous fungi genetics with hands-on experience across multiple species.
  • Proven success in fungal genetic engineering (e.g., DNA delivery, genome editing, CRISPR, transposons) and molecular biology techniques (e.g., cloning, NGS, protein expression).
  • Strong track record of rigorous, high-quality scientific output and record-keeping.
  • Experience mentoring research staff and leading scientific initiatives.
  • Comfort with lab automation and high-throughput screening approaches.
  • Strong analytical skills and the ability to reason from first principles.
  • Creative problem-solving mindset with adaptability to shifting priorities.
  • Excellent communication and collaboration skills, with the ability to work independently and in teams.
  • Passion for impactful research aligned with our mission.

Responsibilities

  • Develop and optimize methods for studying and engineering various filamentous fungi.
  • Design, construct, and test plasmids, genetic parts, and genome-wide perturbation libraries (e.g., transposons, Targetrons, CRISPR).
  • Execute high-throughput cloning methodologies (Golden Gate, isothermal assembly, SLiCE, etc.) and next-generation sequencing (NGS) assays.
  • Discover and characterize novel fungal genetic elements.
  • Collaborate with engineers to integrate automation and high-throughput systems.
  • Stay at the forefront of fungal genetics research, sourcing and implementing cutting-edge techniques.
  • Manage and mentor research staff, ensuring rigorous experimental execution.
  • Maintain meticulous documentation, write SOPs, and prepare internal reports and scientific publications.
  • Effectively communicate findings internally and externally through presentations and manuscripts.

Preferred Qualifications

  • Experience with microscopy, FACS, or microfluidics methods.
  • Experience with isolation of environmental fungal samples.